Kidneys in dogs are located in the mid-abdomen under the spinal column. They are involved in clearing the metabolic waste from the blood, red blood cell production, maintaining electrolyte balance, and regulation of blood pressure. With every heartbeat, the heart pumps 25% of total blood to the kidneys. However, the function of kidneys can be impaired by infections and inflammation which are caused by eating toxins and certain drugs. Symptoms of the illness differ depending upon the cause of the disease. In the case of chronic illness, the symptoms are not obvious and develop slowly. However, in case of acute failure of kidneys, the symptoms are severe and the condition can be life-threatening. Symptoms include vomiting, fatigue, and anorexia. Regular health checkups are vital in finding out kidney infections at an early stage.